Vinblastine Teva Solution for Injection
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of various malignancies including lymphomas and breast carcinoma.
Dosage (summary)
Adults: Initial 3.7 mg/mu00b2 IV, max 18.5 mg/mu00b2 weekly; Children: Initial 2.5 mg/mu00b2 IV, max 12.5 mg/mu00b2 weekly.
Special Populations
- Hepatic impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy and breastfeeding; teratogenic effects.
Key Drug Interactions
- Erythromycin may increase toxicity
- Live vaccines may cause infections
Contraindications
- Hypersensitivity to vinblastine
- Depressed bone marrow function
- Bacterial infections
- Porphyria
- Intrathecal use
Common side effects
- Leucopoenia
- Nausea
- Vomiting
- Alopecia
- Neurotoxicity
Counselling Points
- Avoid contact sports
- Report signs of infection
- Use effective contraception
- Avoid driving if experiencing dizziness
Serious warnings
- Severe toxicity profile
- Risk of infections
- Avoid extravasation
- Carcinogenic potential
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