Adco Zildem SR Capsule
PDF Leaflet Revision Date: 05 July 2024
Clinical Summary
Quick overview from the medicine insert
Indication
Prophylaxis of angina pectoris and treatment of mild to moderate hypertension.
Dosage (summary)
180 mg once or twice daily or 240 mg once daily; start with reduced doses in elderly or impaired function.
Onset of Action / Duration
Onset: 30-60 mins, Duration: 6-8 hours
Special Populations
- Elderly
- Hepatic impairment
- Renal impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy and lactation due to potential teratogenic effects and excretion in milk.
Key Drug Interactions
- Beta-blockers
- Digitalis glycosides
- CYP3A4 inhibitors
- Nitrate derivatives
Contraindications
- Hypersensitivity to diltiazem
- Decompensated cardiac insufficiency
- Severe bradycardia
- AV block
- Pregnancy
- Lactation
Common side effects
- Headache
- Dizziness
- Constipation
- Flushing
- Palpitations
Counselling Points
- Swallow capsules intact
- Avoid grapefruit juice
- Monitor for dizziness
- Report any signs of hypersensitivity
Serious warnings
- Risk of bradycardia
- Monitor renal function
- Caution in hypotension
Important Disclaimer
The Adco Zildem SR Capsule professional information leaflet below is the property of Adcock Ingram and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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