Aluvia 200/50 FC Tablets
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of HIV-1 infection in combination with other antiretroviral agents.
Dosage (summary)
The recommended dose is 400 mg Lopinavir/100 mg Ritonavir (2 tablets) taken orally twice daily with food.
Onset of Action / Duration
Viral load reduction may be observed within 2 weeks, but optimal response may take several months.
Special Populations
- Hepatic impairment
- Renal impairment
- Elderly patients
- Pediatric patients
Pregnancy & Breastfeeding
Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Ritonavir is excreted in breast milk; breastfeeding is not recommended.
Key Drug Interactions
- CYP3A4 inhibitors and inducers
- Anticonvulsants (e.g., phenytoin, carbamazepine)
- Antituberculosis agents (e.g., rifampicin)
- St. John's Wort
- Certain antidepressants (e.g., trazodone)
Contraindications
- Hypersensitivity to Lopinavir, Ritonavir, or any component of the formulation
- Severe hepatic impairment
- Concomitant use with certain medications that are contraindicated due to significant drug interactions
Common side effects
- Diarrhea
- Nausea
- Vomiting
- Abdominal pain
- Fatigue
- Headache
- Hyperlipidemia
Counselling Points
- Take with food to enhance absorption.
- Adhere strictly to the prescribed regimen.
- Report any signs of liver dysfunction (e.g., jaundice, dark urine).
- Inform healthcare provider of all medications being taken.
- Discuss potential side effects and when to seek medical attention.
Serious warnings
- Risk of developing resistance if not taken as prescribed.
- Monitor for signs of pancreatitis.
- Potential for metabolic changes including hyperglycemia and lipid abnormalities.
- Caution in patients with a history of cardiovascular disease.
Important Disclaimer
The Aluvia 200/50 FC Tablets professional information leaflet below is the property of AbbVie and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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