Lopinavir And Ritonavir Cipla 40 mg and 10 mg ORAL PELLETS

    Lopinavir And Ritonavir Cipla 40 mg and 10 mg ORAL PELLETS

    S4
    PDF Leaflet Revision Date: 26 June 2019

    API: Lopinavir, Ritonavir | Company: Cipla Medpro

    Clinical Summary

    Quick overview from the medicine insert

    Indication

    Treatment of HIV infection in combination with other antiretroviral medicines.

    Dosage (summary)

    Adults: 400/100 mg twice daily with food. Children: Dosing varies by weight.

    Special Populations

    • Hepatic impairment
    • Renal impairment

    Pregnancy & Breastfeeding

    Not recommended during pregnancy; avoid breastfeeding to prevent HIV transmission.

    Key Drug Interactions

    • CYP3A inhibitors
    • CYP3A inducers
    • Colchicine
    • Rifampin

    Contraindications

    • Hypersensitivity to lopinavir or ritonavir
    • Severe hepatic insufficiency

    Common side effects

    • Diarrhea
    • Nausea
    • Headache
    • Fatigue
    • Hyperlipidemia

    Counselling Points

    • Take with food
    • Do not alter dose without consulting a doctor
    • Monitor for signs of pancreatitis or liver dysfunction

    Serious warnings

    • Risk of pancreatitis
    • Hepatotoxicity
    • QT interval prolongation
    Important Disclaimer

    The Lopinavir And Ritonavir Cipla 40 mg and 10 mg ORAL PELLETS professional information leaflet below is the property of Cipla Medpro and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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