Ascorbic Acid 500mg/5ml Fresenius Injection
Clinical Summary
Quick overview from the medicine insert
Indication
Severe deficiency states and conditions preventing oral intake.
Dosage (summary)
Up to 1 g daily in divided doses; 200-600 mg therapeutic, 25-75 mg prophylactic.
Special Populations
- Renal impairment
- G6PD deficiency
Pregnancy & Breastfeeding
High doses may harm the fetus; crosses into breast milk.
Key Drug Interactions
- Aspirin
- Alcohol
- Iron
- Phenytoin
- Oral contraceptives
Contraindications
- Hypersensitivity to ascorbic acid
- Hyperoxaluria
Common side effects
- Diarrhoea
- Gastrointestinal disturbances
- Haemolysis in G6PD deficiency
Counselling Points
- Avoid high doses during pregnancy and breastfeeding
- Monitor for side effects with high doses
Serious warnings
- Risk of renal oxalate calculi in renal failure
- Tolerance may develop with high doses
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