Bupivacaine Hcl 0,5 % (10 Ml) Fresenius 10 ml Solution for injection.
PDF Leaflet Revision Date: 17 September 2022
Clinical Summary
Quick overview from the medicine insert
Indication
Used for peripheral nerve block, caudal or epidural block.
Dosage (summary)
Adult doses vary by procedure; max single dose is 150 mg.
Onset of Action / Duration
Onset: 10-40 mins, Duration: several hours
Special Populations
- Elderly
- Debilitated patients
- Severe liver disease
- Severe renal dysfunction
- Pregnant patients
Pregnancy & Breastfeeding
Safety in pregnancy/lactation not established; may affect breastfeeding.
Key Drug Interactions
- Antidysrhythmics (e.g., amiodarone)
- Propranolol
- Calcium-channel blockers
Contraindications
- Hypersensitivity to bupivacaine
- Intravenous regional anaesthesia
- Active CNS disease
- Coagulation disorders
Common side effects
- Bradycardia
- Hypotension
- Nausea
- Urinary retention
- Dizziness
Counselling Points
- Monitor for signs of toxicity
- Avoid in late pregnancy
- Ensure resuscitation equipment is available
- Educate on potential side effects
Serious warnings
- Risk of cardiac arrest
- CNS toxicity
- Severe hypotension
- Accidental intravascular injection
Important Disclaimer
The Bupivacaine Hcl 0,5 % (10 Ml) Fresenius 10 ml Solution for injection. professional information leaflet below is the property of Fresenius Kabi Manufacturing Sa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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