Auro Ampicillin Injection

    Auro Ampicillin Injection

    S4
    PDF Leaflet Revision Date: 02 February 2022


    Clinical Summary

    Quick overview from the medicine insert

    Indication

    Treatment of bacterial infections caused by non-penicillinase-producing ampicillin-sensitive organisms.

    Dosage (summary)

    500 - 1000 mg IV 4-6 times daily; Meningitis: 2 g every 6 hours.

    Onset of Action / Duration

    Onset: 1 hour, Duration: 1-1.5 hours

    Special Populations

    • Elderly
    • Renal impairment

    Pregnancy & Breastfeeding

    Safety in pregnancy and lactation not established; may cause sensitization in infants.

    Key Drug Interactions

    • Increased INR with anticoagulants
    • Decreased efficacy of oral contraceptives
    • Increased risk of rashes with allopurinol

    Contraindications

    • Hypersensitivity to penicillins or cephalosporins
    • Neonates born to hypersensitive mothers

    Common side effects

    • Hypersensitivity reactions
    • Nausea
    • Vomiting
    • Diarrhea

    Counselling Points

    • Observe for allergic reactions
    • Maintain adequate hydration
    • Avoid alcohol during treatment

    Serious warnings

    • Serious hypersensitivity reactions
    • Monitor for Jarisch-Herxheimer reaction in syphilis patients
    Important Disclaimer

    The Auro Ampicillin Injection professional information leaflet below is the property of Aurogen South Africa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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