Trycosil 250 mg/ 500 mg/ 1 g POWDER FOR INJECTION
PDF Leaflet Revision Date: 29/01/2021
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of bacterial infections caused by non-penicillinase-producing ampicillin-sensitive organisms.
Dosage (summary)
500 u2013 1000 mg IV 4-6 times daily; Meningitis: 2 g every 6 hours.
Special Populations
- Elderly
- Renal impairment
Pregnancy & Breastfeeding
Safety not established; may cause sensitization and diarrhea in breastfed infants.
Key Drug Interactions
- Avoid mixing with aminoglycosides
- Increases methotrexate toxicity
- May reduce oral contraceptive efficacy
Contraindications
- Hypersensitivity to penicillins
- Neonates born to hypersensitive mothers
Common side effects
- Nausea
- Vomiting
- Diarrhea
- Skin rashes
- Hypersensitivity reactions
Counselling Points
- Report any allergic reactions
- Maintain adequate fluid intake
- Avoid alcohol during treatment
Serious warnings
- Serious hypersensitivity reactions
- Risk of antibiotic-associated colitis
- Monitor renal function
Important Disclaimer
The Trycosil 250 mg/ 500 mg/ 1 g POWDER FOR INJECTION professional information leaflet below is the property of Aurogen South Africa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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