Avigra FC tablets

Indication

Treatment of erectile dysfunction in adult men.

Dosage (summary)

Initial dose of 50 mg taken approximately 1 hour before sexual activity; may be adjusted to 25 mg or 100 mg based on efficacy and tolerability.

Onset of Action / Duration

Effects typically begin within 30 to 60 minutes and can last for up to 4 hours.

Special Populations

• Elderly patients may require dose adjustment.
• Patients with hepatic impairment should start with a lower dose.
• Patients with renal impairment may require dose adjustment.

Pregnancy & Breastfeeding

Not indicated for use in women; safety during pregnancy and lactation has not been established.

Key Drug Interactions

• Nitrates (e.g., nitroglycerin) can cause severe hypotension when used with sildenafil.
• Alpha-blockers may enhance the hypotensive effects of sildenafil.
• CYP3A4 inhibitors (e.g., ketoconazole, erythromycin) may increase sildenafil levels.

Contraindications

• Hypersensitivity to sildenafil or any component of the formulation.
• Concurrent use of nitrates in any form.
• Severe cardiovascular disorders where sexual activity is inadvisable.

Common side effects

• Headache
• Flushing
• Dyspepsia
• Nasal congestion
• Visual disturbances
• Priapism (prolonged erection)

Counselling Points

• Take sildenafil as needed, not more than once daily.
• Avoid high-fat meals before taking sildenafil as it may delay onset.
• Inform healthcare provider of any other medications being taken.
• Seek immediate medical attention for an erection lasting more than 4 hours.