Breztri Aerosphere
PDF Leaflet Revision Date: 21 October 2025
Clinical Summary
Quick overview from the medicine insert
Indication
Maintenance treatment for COPD.
Dosage (summary)
2 inhalations twice daily.
Onset of Action / Duration
Onset: hours, Duration: 12 hours
Special Populations
- Renal impairment
- Hepatic impairment
- Elderly
Pregnancy & Breastfeeding
Use only if benefits outweigh risks; minimal transfer to breast milk.
Key Drug Interactions
- CYP3A4 inhibitors
- Beta-adrenergic blockers
Contraindications
- Hypersensitivity to components
Common side effects
- Oral candidiasis
- Pneumonia
- Hyperglycaemia
- Anxiety
- Palpitations
Counselling Points
- Instruct on proper inhalation technique
- Do not double dose if missed
- Monitor for worsening symptoms
Serious warnings
- Paradoxical bronchospasm
- Not for acute use
- Potential for pneumonia
Important Disclaimer
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