Bridion 100 mg/mL Solution for Injection
PDF Leaflet Revision Date: 24 November 2022
Clinical Summary
Quick overview from the medicine insert
Indication
Routine and immediate reversal of neuromuscular blockade induced by rocuronium or vecuronium.
Dosage (summary)
4 mg/kg for profound blockade, 2 mg/kg for shallow blockade, 16 mg/kg for immediate reversal.
Special Populations
- Renal impairment
- Hepatic impairment
- Elderly
- Obese patients
- Paediatric patients
Pregnancy & Breastfeeding
Safety in pregnancy not established; caution in breastfeeding due to potential excretion in milk.
Key Drug Interactions
- Toremifene
- Fusidic acid
- Hormonal contraceptives
Contraindications
- Hypersensitivity to sugammadex or inactive ingredients
Common side effects
- Cough
- Airway complications
- Anaesthesia complications
- Procedural hypotension
Counselling Points
- Administer under anaesthetist supervision
- Monitor respiratory function post-reversal
- Inform about potential hypersensitivity reactions
Serious warnings
- Not for reversal of depolarising neuromuscular blocking agents
- Risk of bradycardia
- Monitor for recurrence of neuromuscular blockade
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