Canesten 3 Vc 20mg / 1g Vaginal Cream
Clinical Summary
Quick overview from the medicine insert
Indication
Relief of vaginal itching, burning, and discharge from yeast infections.
Dosage (summary)
Insert 5 g nightly for 3 days; may use 2 applications daily for 6-12 days if needed.
Special Populations
- Girls under 12 years
Pregnancy & Breastfeeding
Use only on medical advice; not recommended in the first trimester.
Key Drug Interactions
- May reduce effectiveness of latex products
Contraindications
- Hypersensitivity to clotrimazole or cetostearyl alcohol
Common side effects
- Burning
- Pruritus
- Rash
Counselling Points
- Use as directed
- Complete treatment even if symptoms improve
- Consult if symptoms recur within 2 months
Serious warnings
- Consult doctor if no improvement in 3 days
- Discontinue if new irritation occurs
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Clinical Particulars
Section 4 of the official insert — extracted exactly as issued, no alterations
4.1 Therapeutic indications
For the relief of vaginal itching, burning and discharge associated with recurrent vaginal yeast infections (vaginal candidiasis).
4.2 Posology and method of administration
Fill enclosed vaginal applicator to the top (i.e. 5 g CANESTEN 3VC). Insert deeply into the vagina every night on retiring for three consecutive days even if symptoms disappear. This is best achieved when lying on the back with the legs pulled in a little towards the body. If individual cases should require it, two applications of 5 g Canesten 3VC can be used daily i.e. one in the morning and one in the evening, for 6 - 12 days. Use even during menstruation, although it is recommended that the treatment should not be carried out during menstruation but should be completed before menstruation begins. For candida vulvitis or vulvo-vaginitis the vaginal cream should be applied thinly to the external genitalia 2 or 3 times a day for 1 - 2 weeks. For the prevention of re-infection, the partner should be treated locally with CANESTEN Cream at the same time in so far as symptoms (e.g. pruritus, inflammation, etc.) are present. CANESTEN preparations are colourless and do not stain the underwear.
4.3 Contraindications
Possible hypersensitivity to clotrimazole and / or cetostearyl alcohol.
4.4 Special warnings and precautions for use
i. Use only if you have already had a vaginal yeast infection diagnosed by a medical practitioner and you have the same symptoms now, otherwise consult your doctor. These symptoms include itching and burning of the vagina and sometimes a white discharge.
ii. If there is no improvement in 3 days or if symptoms have not disappeared within 7 days, then consult a medical practitioner as not all vaginal infections are caused by yeasts.
iii. Consult a medical practitioner if you have abdominal pain, fever or a foul-smelling, or a vaginal discharge before or during use of this medication.
iv. If symptoms recur within 2 months, consult a medical practitioner.
v. Do not use in girls under 12 years of age, except on the advice of a medical practitioner.
vi. If skin rash or new irritation occurs, discontinue use.
vii. Direct contact with Canesten Vaginal Cream may reduce the effectiveness and safety of latex products such as condoms and diaphragms. The effect is temporary and occurs only during treatment.
4.6 Fertility, pregnancy and lactation
Safety has not been established. CANESTEN Vaginal Cream may only be used during pregnancy on the advice of a medical doctor. CANESTEN Vaginal Cream should not be administered to pregnant women during the first trimester, since the safety in this regard has not been established. The possibility of absorption of clotrimazole when administered vaginally cannot be excluded.
4.8 Undesirable effects
Skin and appendages : burning, pruritus, and rash. Contact allergic dermatitis has been reported.
Body as a whole : allergic reaction (syncope, hypotension, dyspnoea, gastrointestinal disorders), pain.
4.9 Overdose
See side-effects and special precautions. In case of accidental ingestion, gastro-intestinal disturbances and central nervous system depression may occur. Treatment is symptomatic and supportive.