Cinited 0,5 Mg 0,5 mg Tablet
PDF Leaflet Revision Date: 04 July 2022
Clinical Summary
Quick overview from the medicine insert
Indication
Relief of acute attacks of gout.
Dosage (summary)
Initial dose: 0.5 to 1 mg (1-2 tablets) immediately, then 0.5 mg (1 tablet) every 2 hours until relief or GI symptoms occur. Max: 6 mg in 3 days.
Onset of Action / Duration
Onset: 12 hours, Duration: 1-2 days
Special Populations
- Renal impairment
- Hepatic impairment
- Elderly
- Debilitated patients
Pregnancy & Breastfeeding
Contraindicated in pregnancy; not recommended during breastfeeding.
Key Drug Interactions
- CYP3A4 inhibitors
- P-glycoprotein inhibitors
- Macrolides
- Statins
- Grapefruit juice
Contraindications
- Hypersensitivity to colchicine
- Pregnancy
- Blood dyscrasia
- Severe renal dysfunction
- Severe hepatic dysfunction
Common side effects
- Nausea
- Vomiting
- Abdominal pain
- Diarrhoea
- Skin rashes
Counselling Points
- Take as prescribed; do not exceed dose
- Report any signs of toxicity immediately
- Avoid grapefruit juice
Serious warnings
- Potentially toxic; narrow therapeutic range
- Severe bone marrow depression
- Monitor blood counts
Important Disclaimer
The Cinited 0,5 Mg 0,5 mg Tablet professional information leaflet below is the property of Aurogen South Africa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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