Claricule 500 mg Powder for solution for Infusion
PDF Leaflet Revision Date: 15 November 2023
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of infections due to susceptible organisms requiring parenteral therapy.
Dosage (summary)
Adults: 1.0 g daily in two doses over 60 mins; adjust for renal impairment.
Special Populations
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Use in pregnancy not established; caution in breastfeeding.
Key Drug Interactions
- Ergot alkaloids
- Oral midazolam
- Statins (lovastatin, simvastatin)
- Colchicine
Contraindications
- Hypersensitivity to macrolides
- QT prolongation history
- Severe hepatic failure with renal impairment
Common side effects
- Abdominal pain
- Diarrhoea
- Nausea
- Vomiting
- Taste perversion
Counselling Points
- Monitor for signs of hepatic disease
- Avoid in pregnancy unless necessary
- Report severe allergic reactions immediately
Serious warnings
- Risk of QT prolongation
- Severe hepatic dysfunction
- Pseudomembranous colitis
Important Disclaimer
The Claricule 500 mg Powder for solution for Infusion professional information leaflet below is the property of Ruby Pharmaceuticals and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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