Cosyrel 5 mg/5 mg, 5 mg/10 mg, 10 mg/5 mg, 10 mg/10 mg film-coated tablets

Cosyrel 5 mg/5 mg, 5 mg/10 mg, 10 mg/5 mg, 10 mg/10 mg film-coated tablets

S3
PDF Leaflet Revision Date: 1 August 2022


Clinical Summary

Quick overview from the medicine insert

Indication

Treatment of hypertension and/or stable coronary artery disease and/or stable chronic heart failure.

Dosage (summary)

One tablet once daily; adjust for renal impairment.

Special Populations

  • Renal impairment
  • Hepatic impairment
  • Elderly

Pregnancy & Breastfeeding

Contraindicated in pregnancy and breastfeeding.

Key Drug Interactions

  • Potassium-sparing diuretics
  • Lithium
  • Aliskiren
  • Sacubitril/valsartan

Contraindications

  • Hypersensitivity
  • Acute heart failure
  • Cardiogenic shock
  • Second or third degree AV block
  • Sick sinus syndrome
  • Symptomatic bradycardia
  • Severe bronchial asthma

Common side effects

  • Headache
  • Dizziness
  • Hypotension
  • Nausea
  • Vomiting

Counselling Points

  • Take in the morning before meals
  • Monitor blood pressure regularly
  • Report any signs of angioedema immediately

Serious warnings

  • Hypotension
  • Angioedema
  • Neutropenia
  • Hepatic failure
Important Disclaimer

The Cosyrel 5 mg/5 mg, 5 mg/10 mg, 10 mg/5 mg, 10 mg/10 mg film-coated tablets professional information leaflet below is the property of Servier Laboratories Sa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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