Cyclocord 500 Mg & 1G 500 mg, 1 g Powder for solution for injection/infusion

    Cyclocord 500 Mg & 1G 500 mg, 1 g Powder for solution for injection/infusion

    S4
    PDF Leaflet Revision Date: 09 May 2023


    Clinical Summary

    Quick overview from the medicine insert

    Indication

    Active treatment of neoplastic diseases and progressive autoimmune diseases.

    Dosage (summary)

    Administered by experienced oncologists; max 50 mg/kg body mass; adjust based on patient response.

    Special Populations

    • Hepatic impairment
    • Renal impairment

    Pregnancy & Breastfeeding

    Contraindicated in first trimester; avoid breastfeeding during treatment.

    Key Drug Interactions

    • Aprepitant
    • Busulfan
    • Ciprofloxacin
    • Azole-antimycotics
    • Warfarin

    Contraindications

    • Hypersensitivity to cyclophosphamide
    • Severe bone marrow suppression
    • Cystitis
    • Infections

    Common side effects

    • Myelosuppression
    • Nausea
    • Vomiting
    • Alopecia
    • Infections

    Counselling Points

    • Avoid pregnancy during treatment
    • Use effective contraception
    • Monitor for infections
    • Stay hydrated

    Serious warnings

    • Anaphylactic reactions
    • Myelosuppression
    • Urotoxicity
    • Cardiotoxicity
    • Pulmonary toxicity
    Important Disclaimer

    The Cyclocord 500 Mg & 1G 500 mg, 1 g Powder for solution for injection/infusion professional information leaflet below is the property of Accord Healthcare and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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