Degranol 200 mg. Tablet
PDF Leaflet Revision Date: 19 April 2020
Clinical Summary
Quick overview from the medicine insert
Indication
Used for epilepsy, bipolar disorder, and neuralgia.
Dosage (summary)
Adults: 100-200 mg once/twice daily, increase to 400 mg 2-3 times daily. Elderly: Start with 100 mg twice daily.
Onset of Action / Duration
Onset: 4-8 hours, Duration: 15 hours
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy and lactation; potential for congenital malformations.
Key Drug Interactions
- CYP3A4 inducers/inhibitors
- Valproic acid
- Macrolide antibiotics
Contraindications
- Hypersensitivity
- Heart block
- Monoamine oxidase inhibitors
- Porphyria
- Bone marrow depression
- Pregnancy
- Liver disease
Common side effects
- Leukopenia
- Dizziness
- Nausea
- Somnolence
- Allergic dermatitis
Counselling Points
- Monitor for mood changes
- Avoid alcohol
- Gradual withdrawal recommended
- Regular blood tests advised
Serious warnings
- Serious dermatologic reactions
- Suicidal behaviour
- Carcinogenicity risk
- Withdrawal seizures
Important Disclaimer
The Degranol 200 mg. Tablet professional information leaflet below is the property of Pharmacare Limited and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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