Dexamethasone 4 Mg/1 Ml Fresenius 4 mg/1 ml Solution for injection.
PDF Leaflet Revision Date: 13 December 2022
Clinical Summary
Quick overview from the medicine insert
Indication
Used as an anti-inflammatory or immunosuppressant in corticosteroid therapy.
Dosage (summary)
Usual adult dosage ranges from 0.5 mg to 20 mg daily, depending on severity.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
- Diabetes mellitus
- Heart failure
Pregnancy & Breastfeeding
May cause fetal adrenal suppression; safety in lactation not established.
Key Drug Interactions
- CYP3A inhibitors may increase side effects
- Barbiturates and rifampicin may reduce effectiveness
- Potassium-depleting diuretics may cause hypokalaemia
Contraindications
- Hypersensitivity to corticosteroids
- Acute infections uncontrolled by antibiotics
- Acute psychosis
- Ocular herpes simplex
- Primary glaucoma
- Osteoporosis
- Peptic ulceration
Common side effects
- Increased susceptibility to infections
- Cushingoid symptoms
- Psychiatric disturbances
- Gastrointestinal issues
- Ocular changes
Counselling Points
- Monitor for signs of infection
- Avoid live vaccines during treatment
- Gradual dosage reduction is essential
- Report any psychiatric symptoms immediately
Serious warnings
- Risk of anaphylactoid reactions
- Cardiovascular collapse with rapid injection
- Adrenal insufficiency upon withdrawal
- Increased risk of infections
Important Disclaimer
The Dexamethasone 4 Mg/1 Ml Fresenius 4 mg/1 ml Solution for injection. professional information leaflet below is the property of Fresenius Kabi Manufacturing Sa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
Healthcare Professionals Only
This content is for registered healthcare professionals
Sign in or create a free account to read the full package insert.
Free for HPCSA-registered professionals. Powered by Medinsert.
