Dolotram 50/100 50 mg/100 mg Injection
PDF Leaflet Revision Date: 24 January 2025
Clinical Summary
Quick overview from the medicine insert
Indication
Management of moderate to severe pain.
Dosage (summary)
Adults: IV/IM/SC: 100 mg; max 400 mg/day. Adjust for elderly and renal/hepatic impairment.
Onset of Action / Duration
Onset: 5-10 mins, Duration: 4-6 hours
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Not recommended in pregnancy or breastfeeding; may cause neonatal withdrawal.
Key Drug Interactions
- CNS depressants
- MAO inhibitors
- SSRIs
- SNRIs
Contraindications
- Hypersensitivity to tramadol
- Respiratory depression
- Increased intracranial pressure
- Severe renal/hepatic impairment
Common side effects
- Nausea
- Dizziness
- Drowsiness
- Constipation
Counselling Points
- Avoid alcohol and CNS depressants
- Do not drive or operate machinery
- Monitor for signs of misuse or dependence
Serious warnings
- Risk of respiratory depression
- Seizures possible
- Potential for addiction and dependence
Important Disclaimer
The Dolotram 50/100 50 mg/100 mg Injection professional information leaflet below is the property of Ranbaxy Pharmaceuticals and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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