Domilo 0,5 mg Capsule
PDF Leaflet Revision Date: 25 July 2021
Clinical Summary
Quick overview from the medicine insert
Indication
Disease modifying therapy for relapsing multiple sclerosis.
Dosage (summary)
1 capsule (0.5 mg) daily; monitor for bradycardia on initiation.
Onset of Action / Duration
Onset: 1 hour, Duration: 1 month
Special Populations
- Renal impairment
- Hepatic impairment
- Elderly patients
- Diabetic patients
Pregnancy & Breastfeeding
Contraindicated in pregnancy; not recommended during breastfeeding.
Key Drug Interactions
- Anti-dysrhythmic medicines
- CYP450 inducers
- Beta blockers
Contraindications
- Hypersensitivity to fingolimod
- Severe active infections
- Pregnancy and lactation
- Immunodeficiency syndrome
Common side effects
- Bradycardia
- Hypertension
- Headache
- Dizziness
- Macular oedema
Counselling Points
- Monitor heart rate for 6 hours post-initiation.
- Report signs of infection immediately.
- Use effective contraception during treatment.
Serious warnings
- Risk of bradydysrhythmia
- Increased risk of infections
- Potential for malignancies
Important Disclaimer
The Domilo 0,5 mg Capsule professional information leaflet below is the property of Adcock Ingram and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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