Eposin 20 mg/ ml Concentrate for Solution
PDF Leaflet Revision Date: 22 April 2024
Clinical Summary
Quick overview from the medicine insert
Indication
Management of testicular and small cell lung tumors, and malignant lymphomas.
Dosage (summary)
50-100 mg/mu00b2/day IV for days 1-5 or 100 mg/mu00b2 on days 1, 3, 5, every 3-4 weeks.
Special Populations
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Teratogenic; avoid in pregnancy and breastfeeding.
Key Drug Interactions
- Ciclosporin
- Cisplatin
- Warfarin
- Phenytoin
Contraindications
- Hypersensitivity
- Severe hepatic dysfunction
- Bone marrow depression
- Renal impairment
- Recent chickenpox or herpes zoster
Common side effects
- Myelosuppression
- Nausea
- Vomiting
- Alopecia
- Hypotension
Counselling Points
- Use effective contraception during and after treatment.
- Monitor for signs of infection or bleeding.
- Avoid live vaccines.
Serious warnings
- Severe myelosuppression
- Anaphylaxis
- Tumor lysis syndrome
Important Disclaimer
The Eposin 20 mg/ ml Concentrate for Solution professional information leaflet below is the property of Teva Pharmaceuticals and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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