Frexivo 250mg SOLUTION FOR INJECTION
PDF Leaflet Revision Date: 14 March 2022
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of oestrogen receptor positive, locally advanced or metastatic breast cancer in postmenopausal women.
Dosage (summary)
500 mg IM as two 5 ml injections, one in each buttock, at 1-month intervals with an additional 500 mg dose 2 weeks after the initial dose.
Special Populations
- Renal impairment
- Hepatic impairment
- Elderly
Pregnancy & Breastfeeding
Contraindicated in pregnancy and breastfeeding; effective contraception required during treatment and for 2 years after.
Contraindications
- Hypersensitivity to ingredients
- Severe hepatic impairment
- Pregnancy
- Breastfeeding
Common side effects
- Injection site reactions
- Asthenia
- Nausea
- Hypersensitivity reactions
- Joint pain
- Rash
- Hot flushes
Counselling Points
- Administer slowly (1-2 mins/injection)
- Avoid mixing with other medications
- Monitor for hypersensitivity reactions
Serious warnings
- Caution in hepatic impairment
- Risk of osteoporosis
- Injection site related events
Important Disclaimer
The Frexivo 250mg SOLUTION FOR INJECTION professional information leaflet below is the property of Astrazeneca Pharmaceuticals and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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