Kizofrin 25 mg / 100 mg / 200 mg / 300 mg TABLETS
PDF Leaflet Revision Date: 05 December 2022
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of schizophrenia and manic episodes associated with bipolar disorder.
Dosage (summary)
Adults: Start at 50 mg, titrate to 300-450 mg/day for schizophrenia; 100 mg to 400 mg/day for bipolar disorder.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Contraindicated due to lack of safety data.
Key Drug Interactions
- CYP3A4 inhibitors
- Antihypertensives
- Dopaminergics
Contraindications
- Hypersensitivity
- Pregnancy
- Lactation
- Severe liver/renal impairment
Common side effects
- Somnolence
- Dizziness
- Tachycardia
- Weight gain
Counselling Points
- Monitor for mood changes
- Avoid driving if drowsy
- Regular glucose monitoring for diabetics
Serious warnings
- Risk of suicidal ideation
- Hyperglycaemia
- Neuroleptic malignant syndrome
Important Disclaimer
The Kizofrin 25 mg / 100 mg / 200 mg / 300 mg TABLETS professional information leaflet below is the property of Aurogen South Africa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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