Klacid Xl 500mg Tablet
PDF Leaflet Revision Date: 01 December 2006
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of respiratory and skin infections.
Dosage (summary)
500 mg once daily with food; may increase to 1000 mg for severe infections.
Special Populations
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Not established; use with caution in pregnancy and is excreted in breast milk.
Key Drug Interactions
- Warfarin
- Colchicine
- CYP3A substrates
Contraindications
- Hypersensitivity to macrolides
- Creatinine clearance < 30 ml/min
Common side effects
- Abdominal pain
- Nausea
- Diarrhoea
- Dizziness
- Headache
Counselling Points
- Take with food
- Monitor for signs of liver dysfunction
- Avoid in severe renal impairment
Serious warnings
- Pseudomembranous colitis
- Colchicine toxicity
- QT prolongation
Important Disclaimer
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