Lamorola 25mg. 50mg. 100mg. 200mg Tablet.
Clinical Summary
Quick overview from the medicine insert
Indication
Monotherapy or add-on treatment of partial epilepsy and Lennox-Gastaut syndrome.
Dosage (summary)
Adults: Start at 25 mg/day, increase to 100-200 mg/day. Children: 2 mg/kg/day, max 15 mg/kg/day.
Special Populations
- Hepatic impairment
- Renal impairment
- Elderly patients
Pregnancy & Breastfeeding
Safety in pregnancy and breastfeeding not established.
Key Drug Interactions
- Sodium valproate increases half-life
- Enzyme inducers decrease half-life
Contraindications
- Hypersensitivity to lamotrigine
- Hepatic or renal impairment
- Age over 65
Common side effects
- Rash
- Headache
- Dizziness
- Nausea
- Insomnia
Counselling Points
- Report any rash immediately
- Avoid abrupt discontinuation
- Monitor weight in children
Serious warnings
- Risk of serious skin reactions
- Abrupt withdrawal may cause rebound seizures
- Monitor for HLH symptoms
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