Leucovorin 100 Mg/10 Ml; 200 Mg/20 Ml; 300 Mg/30 Ml Abic 100 mg/10 ml; 200 mg/20 ml; 300 mg/30 m Erythopoietics (Haematinics)
PDF Leaflet Revision Date: 28 June 2024
Clinical Summary
Quick overview from the medicine insert
Indication
Counteracts toxicity of folic acid antagonists and treats megaloblastic anemia.
Dosage (summary)
1-15 mg daily IM for anemia; 10-15 mg/mu00b2 every 6 hours for methotrexate rescue.
Special Populations
- Renal impairment
- Elderly
Pregnancy & Breastfeeding
Use with caution; consult healthcare provider.
Key Drug Interactions
- Intensifies toxicity of 5-fluorouracil
- May negate methotrexate effect
Contraindications
- Hypersensitivity
- Pernicious anemia
- Vitamin B12 deficiency
Common side effects
- Hypersensitivity reactions
- Thrombocytosis
Counselling Points
- Administer leucovorin after methotrexate
- Monitor renal function and methotrexate levels
Serious warnings
- Monitor for gastrointestinal toxicity
- May increase seizure frequency in children
Important Disclaimer
The Leucovorin 100 Mg/10 Ml; 200 Mg/20 Ml; 300 Mg/30 Ml Abic 100 mg/10 ml; 200 mg/20 ml; 300 mg/30 m Erythopoietics (Haematinics) professional information leaflet below is the property of Teva Pharmaceuticals and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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