Licax 250 Mg/ 500 Mg 250 mg/ 500 mg POWDER FOR INJECTION

    Licax 250 Mg/ 500 Mg 250 mg/ 500 mg POWDER FOR INJECTION

    S4
    PDF Leaflet Revision Date: 05/02/2021


    Clinical Summary

    Quick overview from the medicine insert

    Indication

    Infections caused by penicillinase-producing staphylococci.

    Dosage (summary)

    250 mg IM every 4-6 hours; 500 mg IV every 4-6 hours.

    Onset of Action / Duration

    Onset: 1 hour, Duration: 6 hours

    Special Populations

    • Jaundiced neonates

    Pregnancy & Breastfeeding

    Safety not established; crosses placenta and into breast milk.

    Key Drug Interactions

    • Bacteriostatic antibacterials
    • Anticoagulants
    • Oral contraceptives
    • Methotrexate

    Contraindications

    • Hypersensitivity to cloxacillin
    • History of penicillin allergy
    • Neonates of penicillin-sensitive mothers

    Common side effects

    • Skin rashes
    • Angioedema
    • Bronchospasm
    • Anaphylaxis
    • Convulsions

    Counselling Points

    • Monitor for allergic reactions
    • Take on an empty stomach for better absorption
    • Avoid use in certain populations

    Serious warnings

    • Risk of neurotoxicity in high doses
    • Sensitivity reactions may occur
    Important Disclaimer

    The Licax 250 Mg/ 500 Mg 250 mg/ 500 mg POWDER FOR INJECTION professional information leaflet below is the property of Aurogen South Africa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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