Lokit Od 20 mg, 40mg Hard gelatine capsules
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of duodenal ulcer, gastric ulcer, reflux oesophagitis, and Zollinger-Ellison syndrome.
Dosage (summary)
20 mg once daily for duodenal ulcers; 40 mg for refractory cases; 20 mg for gastric ulcers and reflux.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Safety in pregnancy and breastfeeding not established.
Key Drug Interactions
- Nelfinavir
- Atazanavir
- Clopidogrel
- Digoxin
- Phenytoin
Contraindications
- Hypersensitivity to omeprazole
- Concomitant use with nelfinavir
Common side effects
- Headache
- Abdominal pain
- Constipation
- Diarrhoea
- Nausea
Counselling Points
- Take before meals
- Monitor for signs of hypomagnesaemia
- Avoid alcohol
Serious warnings
- Risk of hypomagnesaemia
- Increased risk of fractures
- Potential for Clostridium difficile-associated diarrhoea
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