Lucrin Depot 3,75 Mg Pds 3,75 mg Lyophilised microspheres and sterile diluent suspension for injection
PDF Leaflet Revision Date: 20 October 2025
Clinical Summary
Quick overview from the medicine insert
Indication
Management of endometriosis, prostate cancer, breast cancer, and central precocious puberty.
Dosage (summary)
3.75 mg subcutaneously once a month for adults; individualized for children based on weight.
Special Populations
- Children
- Elderly
Pregnancy & Breastfeeding
Contraindicated in pregnancy and breastfeeding.
Key Drug Interactions
- QT prolonging drugs
- Bupropion
- SSRIs
Contraindications
- Hypersensitivity to leuprolide
- Undiagnosed abnormal vaginal bleeding
- Pregnancy
- Breastfeeding
Common side effects
- Hot flushes
- Weight gain
- Headache
- Nausea
- Fatigue
Counselling Points
- Use non-hormonal contraception
- Report any unusual symptoms
- Adhere to injection schedule
Serious warnings
- Risk of convulsions
- Decreased bone mineral density
- Potential exacerbation of symptoms during initial therapy
Important Disclaimer
The Lucrin Depot 3,75 Mg Pds 3,75 mg Lyophilised microspheres and sterile diluent suspension for injection professional information leaflet below is the property of AbbVie and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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