Macaine Hcl 0,5 % Injection 1 mL Injection
PDF Leaflet Revision Date: 27 October 2025
Clinical Summary
Quick overview from the medicine insert
Indication
Peripheral nerve block, caudal or epidural block.
Dosage (summary)
Varies by procedure; max 150 mg per injection, reduce for elderly.
Special Populations
- Elderly
- Debilitated patients
- Children under 12
Pregnancy & Breastfeeding
Safety in pregnancy/lactation not established; may affect fetus.
Key Drug Interactions
- Antidysrhythmics
- Propranolol
- Calcium-channel blockers
Contraindications
- Hypersensitivity to bupivacaine
- Active CNS disease
- Coagulation disorders
Common side effects
- Dizziness
- Nausea
- Urinary retention
- Bradycardia
Counselling Points
- Avoid accidental intravascular injection
- Monitor for CNS effects
- Use caution in elderly and debilitated patients
Serious warnings
- Risk of cardiac arrest
- Systemic toxicity
- Hypotension
Important Disclaimer
The Macaine Hcl 0,5 % Injection 1 mL Injection professional information leaflet below is the property of Adcock Ingram Critical Care and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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