Metformin 500, 850 & 1000 Mg Pharmc 500mg, 850 mg, 1000 mg Tablet

Metformin 500, 850 & 1000 Mg Pharmc 500mg, 850 mg, 1000 mg Tablet

S3
PDF Leaflet Revision Date: 03 October 2023


Clinical Summary

Quick overview from the medicine insert

Indication

Treatment of type 2 diabetes mellitus.

Dosage (summary)

Adults: 500 mg three times daily or 850/1000 mg twice daily with meals. Max: 2550 mg/day.

Onset of Action / Duration

Onset: Few days, Duration: Up to 2 weeks for full effect.

Special Populations

  • Elderly
  • Renal impairment

Pregnancy & Breastfeeding

Not recommended in pregnancy; use insulin instead. Limited data on breastfeeding.

Key Drug Interactions

  • Alcohol
  • Iodinated contrast agents
  • NSAIDs
  • ACE inhibitors

Contraindications

  • Hypersensitivity
  • Diabetic ketoacidosis
  • Renal failure
  • Hepatic insufficiency
  • Pregnancy

Common side effects

  • Nausea
  • Vomiting
  • Diarrhoea
  • Abdominal pain
  • Loss of appetite

Counselling Points

  • Take with meals
  • Monitor blood glucose
  • Avoid alcohol
  • Assess vitamin B12 levels annually

Serious warnings

  • Lactic acidosis risk
  • Monitor renal function
  • Caution in heart failure
Important Disclaimer

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