Nexiam 20 mg, 40 mg Gastric resistant tablet.
PDF Leaflet Revision Date: 24 November 2025
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of gastro-oesophageal reflux disease (GORD) and prevention of gastric ulcers.
Dosage (summary)
Adults: 20-40 mg once daily; adjust for specific conditions.
Onset of Action / Duration
Onset: 1 hour, Duration: 24 hours
Special Populations
- Renal impairment
- Hepatic impairment
- Elderly
Pregnancy & Breastfeeding
Safety not established during pregnancy and lactation.
Key Drug Interactions
- Clopidogrel
- Warfarin
- Digoxin
Contraindications
- Hypersensitivity to esomeprazole
- Concomitant use with atazanavir or nelfinavir
Common side effects
- Headache
- Abdominal pain
- Diarrhoea
- Nausea
Counselling Points
- Take whole with liquid
- Monitor for severe skin reactions
- Avoid alcohol
Serious warnings
- Risk of serious skin reactions
- Hypomagnesaemia
- Increased risk of gastrointestinal infections
Important Disclaimer
The Nexiam 20 mg, 40 mg Gastric resistant tablet. professional information leaflet below is the property of Astrazeneca Pharmaceuticals and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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