Nexiam 5 mg, 2,5 mg Sachets

    Nexiam 5 mg, 2,5 mg Sachets

    S4
    PDF Leaflet Revision Date: 20 May 2021


    Clinical Summary

    Quick overview from the medicine insert

    Indication

    Treatment of Gastro-Oesophageal Reflux Disease (GORD).

    Dosage (summary)

    2.5 mg to 10 mg once daily for infants; 20 mg to 40 mg once daily for adults.

    Onset of Action / Duration

    Onset: 1 hour, Duration: 13-17 hours.

    Special Populations

    • Elderly
    • Renal impairment
    • Hepatic impairment

    Pregnancy & Breastfeeding

    Safety not established during pregnancy and lactation.

    Key Drug Interactions

    • Inhibits CYP2C19
    • Increased digoxin absorption
    • Increased warfarin INR

    Contraindications

    • Hypersensitivity to esomeprazole or benzimidazoles

    Common side effects

    • Headache
    • Abdominal pain
    • Diarrhoea
    • Nausea/vomiting

    Counselling Points

    • Take with non-carbonated water.
    • Monitor for gastrointestinal symptoms.
    • Report any allergic reactions.

    Serious warnings

    • May mask gastric malignancy symptoms
    • Increased risk of gastrointestinal infections
    Important Disclaimer

    The Nexiam 5 mg, 2,5 mg Sachets professional information leaflet below is the property of Astrazeneca Pharmaceuticals and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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