Ondansetron 4 Mg/2 Ml Fresenius, Ondansetron 8 Mg/4 Ml Fresenius 4 mg/2 ml, 8 mg/4 ml Solution for injection or infusion
Clinical Summary
Quick overview from the medicine insert
Indication
Management of nausea and vomiting induced by chemotherapy, radiotherapy, and post-operative nausea and vomiting.
Dosage (summary)
Adults: 8 mg IV/IM before treatment; max 16 mg for highly emetogenic chemotherapy. Elderly: max 8 mg IV for patients u226575 years.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Contraindicated in the first 12 weeks of pregnancy and for PONV during pregnancy; avoid breastfeeding.
Key Drug Interactions
- QT prolonging medicines
- Serotonergic medicines
- Apomorphine
Contraindications
- Hypersensitivity to ondansetron
- Congenital long QT syndrome
Common side effects
- Headache
- Constipation
- Dizziness
- Visual disturbances
Counselling Points
- Avoid driving if experiencing dizziness
- Report any signs of allergic reactions
- Monitor for signs of QT prolongation
Serious warnings
- QT prolongation
- Risk of myocardial ischaemia
- Serotonin syndrome
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