Oxaliplatin Key 50 mg, 100 mg Powder for injection
PDF Leaflet Revision Date: 19 April 2024
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of metastatic colorectal cancer and adjuvant treatment of colon cancer.
Dosage (summary)
85 mg/mu00b2 IV every 2 weeks for adults.
Special Populations
- Renal impairment
- Hepatic impairment
- Elderly patients
Pregnancy & Breastfeeding
Contraindicated in pregnancy and breastfeeding.
Key Drug Interactions
- Bone marrow depressants
- Anticoagulants
- Nephrotoxic medicines
- Ototoxic medicines
- Live vaccines
Contraindications
- Hypersensitivity to oxaliplatin
- Pregnancy and breastfeeding
- Bone marrow failure
- Myelosuppression
- Peripheral sensory neuropathy
- Severe renal impairment
- Pulmonary toxicity
Common side effects
- Nausea
- Vomiting
- Diarrhoea
- Neutropenia
- Peripheral sensory neuropathy
Counselling Points
- Avoid cold exposure post-infusion.
- Monitor for signs of allergic reactions.
- Use effective contraception during treatment.
- Inform about potential for persistent neuropathy.
Serious warnings
- Serious allergic reactions
- Neurological toxicity
- Gastrointestinal complications
- QT prolongation
- Rhabdomyolysis
Important Disclaimer
The Oxaliplatin Key 50 mg, 100 mg Powder for injection professional information leaflet below is the property of Key Oncologics and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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