Palonosetron 250 μg/ 5 mL Solution for injection
PDF Leaflet Revision Date: 09 December 2022
Clinical Summary
Quick overview from the medicine insert
Indication
Prevention of acute nausea and vomiting from highly and moderately emetogenic chemotherapy.
Dosage (summary)
Adults: 250 u03bcg IV bolus 30 mins before chemotherapy.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Not recommended in pregnancy; breastfeeding should be discontinued during therapy.
Key Drug Interactions
- CYP2D6 inducers/inhibitors
- Serotonergic medicines
Contraindications
- Hypersensitivity to palonosetron
Common side effects
- Headache
- Dizziness
- Constipation
Counselling Points
- Monitor for serotonin syndrome symptoms
- Caution with driving until effects are known
Serious warnings
- Risk of serotonin syndrome
- QT interval prolongation caution
Important Disclaimer
The Palonosetron 250 μg/ 5 mL Solution for injection professional information leaflet below is the property of Cipla Medpro and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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