Palonosetron 0,05 Mg/Ml Fresenius 0,05 mg/mL Solution for injection
PDF Leaflet Revision Date: 19 April 2022
Clinical Summary
Quick overview from the medicine insert
Indication
Prevention of acute and moderately emetogenic chemotherapy-induced nausea and vomiting.
Dosage (summary)
250 micrograms IV bolus 30 mins before chemotherapy.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Not recommended in pregnancy; discontinue breastfeeding during therapy.
Key Drug Interactions
- Serotonergic medicines
- CYP2D6 inducers/inhibitors
- Corticosteroids
Contraindications
- Hypersensitivity to palonosetron or excipients
Common side effects
- Headache
- Constipation
Counselling Points
- Monitor for serotonin syndrome symptoms
- Caution with driving or operating machinery
Serious warnings
- Serotonin syndrome risk
- QT interval caution
Important Disclaimer
The Palonosetron 0,05 Mg/Ml Fresenius 0,05 mg/mL Solution for injection professional information leaflet below is the property of Fresenius Kabi South Africa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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