Phenylephrine Phenylephrine 50 Μg/Ml 50 /mL Solution for Injection in prefilled syringe
PDF Leaflet Revision Date: 17 June 2025
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of hypotension during spinal, epidural or general anaesthesia.
Dosage (summary)
Adults: 50-100 micrograms IV, repeat as needed; max 100 micrograms per bolus.
Onset of Action / Duration
Onset: Immediate, Duration: 15-20 minutes
Special Populations
- Renal impairment
- Hepatic impairment
- Elderly
Pregnancy & Breastfeeding
Safety in pregnancy not established; use with caution. Not recommended during lactation.
Key Drug Interactions
- MAO inhibitors
- Indirect sympathomimetics
- Alpha sympathomimetics
Contraindications
- Hypersensitivity to phenylephrine
- Severe hypertension
- Peripheral vascular disease
- Heart block
- Severe hyperthyroidism
Common side effects
- Bradycardia
- Hypertensive episodes
- Nausea
- Vomiting
Counselling Points
- Report any adverse reactions
- Avoid use in severe hypertension
- Monitor for bradycardia
Serious warnings
- Monitor arterial blood pressure
- Risk of tissue necrosis with extravasation
- Caution in patients with coronary heart disease
Important Disclaimer
The Phenylephrine Phenylephrine 50 Μg/Ml 50 /mL Solution for Injection in prefilled syringe professional information leaflet below is the property of Equity Pharmaceuticals and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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