Phesgo 600/600 mg and 1 200/600 mg Subcutaneous injection
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of HER2-positive breast cancer.
Dosage (summary)
Loading dose: 1200 mg/600 mg SC, Maintenance: 600 mg/600 mg SC every 3 weeks.
Special Populations
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Avoid during pregnancy; may cause fetal harm. Discontinue breastfeeding during treatment and for 7 months after.
Key Drug Interactions
- Docetaxel
- Anthracyclines
Contraindications
- Hypersensitivity to pertuzumab or trastuzumab
Common side effects
- Injection site reactions
- Fatigue
- Anemia
- Dyspnea
Counselling Points
- Monitor for injection-related reactions
- Use effective contraception during treatment
- Report any signs of heart failure.
Serious warnings
- Cardiomyopathy
- Embryo-fetal toxicity
- Pulmonary toxicity
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