Phesgo 600/600 mg and 1 200/600 mg Subcutaneous injection

    Phesgo 600/600 mg and 1 200/600 mg Subcutaneous injection

    S4
    PDF Leaflet Revision Date: 20 June 2023


    Clinical Summary

    Quick overview from the medicine insert

    Indication

    Treatment of HER2-positive breast cancer.

    Dosage (summary)

    Loading dose: 1200 mg/600 mg SC, Maintenance: 600 mg/600 mg SC every 3 weeks.

    Special Populations

    • Renal impairment
    • Hepatic impairment

    Pregnancy & Breastfeeding

    Avoid during pregnancy; may cause fetal harm. Discontinue breastfeeding during treatment and for 7 months after.

    Key Drug Interactions

    • Docetaxel
    • Anthracyclines

    Contraindications

    • Hypersensitivity to pertuzumab or trastuzumab

    Common side effects

    • Injection site reactions
    • Fatigue
    • Anemia
    • Dyspnea

    Counselling Points

    • Monitor for injection-related reactions
    • Use effective contraception during treatment
    • Report any signs of heart failure.

    Serious warnings

    • Cardiomyopathy
    • Embryo-fetal toxicity
    • Pulmonary toxicity
    Important Disclaimer

    The Phesgo 600/600 mg and 1 200/600 mg Subcutaneous injection professional information leaflet below is the property of Roche Products and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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