Rivotril Range 0.5 mg/ 2 mg/ 1 mg/m_/ 2.5 mg/m_ Tablets. Injection. Drops

    Rivotril Range 0.5 mg/ 2 mg/ 1 mg/m_/ 2.5 mg/m_ Tablets. Injection. Drops

    S5
    PDF Leaflet Revision Date: 02 March 2022

    API: Clonazepam | Company: Roche Products

    Clinical Summary

    Quick overview from the medicine insert

    Indication

    Epilepsy and Panic Disorder.

    Dosage (summary)

    Adults: Initial 1.5 mg/day, max 20 mg/day. Adjust based on response.

    Onset of Action / Duration

    Onset: 30-60 mins, Duration: 8-12 hours.

    Special Populations

    • Elderly
    • Renal impairment
    • Hepatic impairment

    Pregnancy & Breastfeeding

    Use only if necessary in pregnancy; contraindicated in breastfeeding.

    Key Drug Interactions

    • CNS depressants
    • Phenytoin
    • Valproate

    Contraindications

    • Hypersensitivity to clonazepam
    • Severe respiratory insufficiency
    • Severe hepatic impairment
    • Acute narrow angle glaucoma
    • Sleep apnoea

    Common side effects

    • Somnolence
    • Headache
    • Dizziness
    • Fatigue
    • Nausea

    Counselling Points

    • Avoid alcohol
    • Monitor for sedation
    • Gradual dose tapering recommended

    Serious warnings

    • Risk of dependence
    • Withdrawal symptoms
    • Paradoxical reactions
    Important Disclaimer

    The Rivotril Range 0.5 mg/ 2 mg/ 1 mg/m_/ 2.5 mg/m_ Tablets. Injection. Drops professional information leaflet below is the property of Roche Products and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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