Tecentriq 840 Mg. Tecentriq 1 200 Mg. 840 mg. 1 200 mg Concentrate for solution for infusion

    Tecentriq 840 Mg. Tecentriq 1 200 Mg. 840 mg. 1 200 mg Concentrate for solution for infusion

    S4
    PDF Leaflet Revision Date: 13 February 2025

    API: Atezolizumab | Company: Roche Products

    Clinical Summary

    Quick overview from the medicine insert

    Indication

    Treatment of various cancers including metastatic urothelial carcinoma and non-small cell lung cancer.

    Dosage (summary)

    840 mg every 2 weeks or 1,200 mg every 3 weeks; adjust based on indication.

    Special Populations

    • Renal impairment
    • Hepatic impairment
    • Geriatric patients

    Pregnancy & Breastfeeding

    Contraindicated in pregnancy; avoid breastfeeding during treatment and for 5 months after.

    Key Drug Interactions

    • Avoid systemic corticosteroids before starting
    • No significant drug-drug interactions expected

    Contraindications

    • Hypersensitivity to atezolizumab
    • Use of live vaccines

    Common side effects

    • Fatigue
    • Nausea
    • Diarrhea
    • Rash
    • Infusion-related reactions

    Counselling Points

    • Monitor for signs of immune-mediated reactions
    • Advise on contraception during treatment
    • Inform about potential infusion reactions

    Serious warnings

    • Immune-mediated pneumonitis
    • Hepatitis
    • Colitis
    • Endocrinopathies
    • Severe cutaneous adverse reactions
    Important Disclaimer

    The Tecentriq 840 Mg. Tecentriq 1 200 Mg. 840 mg. 1 200 mg Concentrate for solution for infusion professional information leaflet below is the property of Roche Products and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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