Pretomanid Mylan 200 mg Tablets
PDF Leaflet Revision Date: 30 May 2023
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of XDR or treatment-intolerant MDR tuberculosis.
Dosage (summary)
200 mg orally once daily for 26 weeks, in combination with bedaquiline and linezolid.
Special Populations
- Elderly
- Hepatic impairment
- Renal impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy and lactation.
Key Drug Interactions
- CYP3A4 inducers (e.g., rifampicin, efavirenz)
Contraindications
- Hypersensitivity to pretomanid
- Use with contraindicated medications
- Pregnancy and lactation
Common side effects
- Nausea
- Fatigue
- Peripheral neuropathy
- Visual impairment
- Increased transaminases
Counselling Points
- Take with food.
- Adhere to the full course of therapy.
- Monitor for visual changes.
- Avoid alcohol and hepatotoxic medications.
Serious warnings
- Hepatotoxicity
- Myelosuppression
- QT prolongation
- Lactic acidosis
Important Disclaimer
The Pretomanid Mylan 200 mg Tablets professional information leaflet below is the property of Mylan and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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