Prevymis 240 Mg Tablets 240 mg Tablet
PDF Leaflet Revision Date: 15 November 2022
Clinical Summary
Quick overview from the medicine insert
Indication
Prophylaxis of CMV reactivation in adult HSCT recipients.
Dosage (summary)
480 mg once daily, starting post-HSCT.
Onset of Action / Duration
Onset: 28 days, Duration: 100 days
Special Populations
- Elderly
- Hepatic impairment
- Renal impairment
Pregnancy & Breastfeeding
Not recommended in pregnancy; avoid breastfeeding.
Key Drug Interactions
- CYP3A substrates
- Ciclosporin
- Statins
Contraindications
- Hypersensitivity
- Pimozide
- Ergot alkaloids
- St. John's wort
- Ciclosporin combination
Common side effects
- Nausea
- Diarrhoea
- Vomiting
Counselling Points
- Take missed dose as soon as remembered
- Do not double dose
- Monitor for nausea and vomiting
Serious warnings
- Monitor CMV DNA
- Risk of adverse reactions with interactions
Important Disclaimer
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