Propofol Mct/Lct 1 % Fresenius 10 mg per mL Emulsion for injection or infusion
PDF Leaflet Revision Date: 17 July 2024
Clinical Summary
Quick overview from the medicine insert
Indication
Short-acting intravenous general anaesthetic.
Dosage (summary)
Induction: 1.5-2.5 mg/kg; Maintenance: 4-12 mg/kg/h.
Onset of Action / Duration
Onset: 30 secs, Duration: varies.
Special Populations
- Elderly patients
- Renal impairment
- Hepatic impairment
- Cardiac insufficiency
Pregnancy & Breastfeeding
Contraindicated in pregnancy; avoid breastfeeding for 24 hours post-administration.
Key Drug Interactions
- CNS depressants (e.g., benzodiazepines, opioids)
- Rifampicin
- Valproate
Contraindications
- Hypersensitivity to propofol or excipients
- Children < 3 years
- Sedation in children < 16 years
Common side effects
- Hypotension
- Bradycardia
- Nausea
- Transient apnoea
Counselling Points
- Avoid driving or operating machinery for 24 hours.
- Monitor for signs of respiratory depression.
- Do not consume alcohol for 24 hours post-administration.
Serious warnings
- Respiratory depression
- Propofol infusion syndrome
- Anaphylactic reactions
Important Disclaimer
The Propofol Mct/Lct 1 % Fresenius 10 mg per mL Emulsion for injection or infusion professional information leaflet below is the property of Fresenius Kabi South Africa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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