Rifapentine 300 Adco 300 mg FC tablets
PDF Leaflet Revision Date: 27 January 2026
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of latent tuberculosis infection in high-risk patients.
Dosage (summary)
Once-weekly for 12 weeks, max 900 mg based on weight.
Special Populations
- Elderly
- Hepatic impairment
- Renal impairment
Pregnancy & Breastfeeding
Not recommended in pregnancy; safety in lactation not established.
Key Drug Interactions
- CYP3A4 inducers/inhibitors
- Hormonal contraceptives
- Digoxin
Contraindications
- Hypersensitivity to rifapentine
- Porphyria
- Liver disease
Common side effects
- Hypersensitivity
- Nausea
- Headache
- Hepatitis
Counselling Points
- Take with food
- Monitor for liver function
- May cause red-orange discolouration of body fluids
Serious warnings
- Hepatotoxicity
- Severe cutaneous adverse reactions
- Clostridium difficile-associated diarrhoea
Important Disclaimer
The Rifapentine 300 Adco 300 mg FC tablets professional information leaflet below is the property of Adcock Ingram and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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