Subrinex 200 mg/2 mL Solution for injection
PDF Leaflet Revision Date: 07.2024
Clinical Summary
Quick overview from the medicine insert
Indication
Routine and immediate reversal of neuromuscular blockade induced by rocuronium or vecuronium.
Dosage (summary)
Adults: 4 mg/kg for profound blockade, 2 mg/kg for shallow blockade, 16 mg/kg for immediate reversal at 3 mins.
Special Populations
- Renal impairment
- Elderly patients
- Obese patients
- Hepatic impairment
Pregnancy & Breastfeeding
Safety in pregnancy not established; excretion in breast milk expected.
Key Drug Interactions
- Toremifene
- Fusidic acid
- Hormonal contraceptives
Contraindications
- Hypersensitivity to sugammadex or excipients
Common side effects
- Cough
- Dysgeusia
- Headache
- Marked bradycardia
Counselling Points
- Monitor for recurrence of neuromuscular blockade
- Caution in renal impairment
- Inform about potential hypersensitivity reactions
Serious warnings
- Not for use with depolarising neuromuscular blockers
- Risk of recurrence of neuromuscular blockade
- Marked bradycardia observed
Important Disclaimer
The Subrinex 200 mg/2 mL Solution for injection professional information leaflet below is the property of Abex Pharmaceutica and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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