Tomexa 200 μg/2mL; 400 μg/4mL; 1000 μg/10 mL Concentrate for solution for infusion
PDF Leaflet Revision Date: 24 February 2025
Clinical Summary
Quick overview from the medicine insert
Indication
Sedation in ICU and monitored anaesthesia care.
Dosage (summary)
Loading: 1.0 mcg/kg over 10 mins; Maintenance: 0.2-0.7 mcg/kg/hr.
Special Populations
- Elderly
- Hepatic impairment
- Renal impairment
Pregnancy & Breastfeeding
Not recommended in pregnancy; excreted in breast milk.
Key Drug Interactions
- Enhanced effects with sedatives and opioids
- Caution with beta blockers
Contraindications
- Hypersensitivity to dexmedetomidine
- Sepsis
- Unstable trauma
- Hypovolaemia
- Heart block
- Uncontrolled cardiac failure
Common side effects
- Hypotension
- Bradycardia
- Hypertension
- Nausea
- Dry mouth
Counselling Points
- Avoid driving for 24 hours post-sedation
- Monitor for signs of agitation after stopping
- Fluid supplementation is necessary
Serious warnings
- Serious bradycardia and sinus arrest
- Careful titration in elderly
- Continuous monitoring required
Important Disclaimer
The Tomexa 200 μg/2mL; 400 μg/4mL; 1000 μg/10 mL Concentrate for solution for infusion professional information leaflet below is the property of Pharmacorp and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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