Topamaxa Tablets Range 25 mg, 50 mg, 100 mg, 200 mg Tablet.
PDF Leaflet Revision Date: 03 May 2022
Clinical Summary
Quick overview from the medicine insert
Indication
Monotherapy and adjunctive therapy for epilepsy.
Dosage (summary)
Adults: Start at 25 mg nightly, titrate to 100-500 mg/day. Children: Start at 0.5-1 mg/kg nightly, titrate to 100-400 mg/day.
Special Populations
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Teratogenic in animals; potential fetal harm in humans. Use only if benefits outweigh risks.
Key Drug Interactions
- Phenytoin
- Carbamazepine
- Valproic acid
- Oral contraceptives
Contraindications
- Hypersensitivity
- Children under 2 years
Common side effects
- Anorexia
- Dizziness
- Somnolence
- Depression
- Weight decreased
Counselling Points
- Monitor for mood changes
- Maintain hydration
- Avoid CNS depressants
- Report visual disturbances
Serious warnings
- Acute myopia and secondary angle closure glaucoma
- Metabolic acidosis
- Suicidal ideation
- Serious skin reactions
Important Disclaimer
The Topamaxa Tablets Range 25 mg, 50 mg, 100 mg, 200 mg Tablet. professional information leaflet below is the property of Janssen Pharmaceutica and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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