Tramacet 37.5 mg / 25 mg Tablets
PDF Leaflet Revision Date: 15 February 2016
Clinical Summary
Quick overview from the medicine insert
Indication
Management of moderate to moderately-severe pain in adults.
Dosage (summary)
1 or 2 tablets every 4 to 6 hours as needed, max 8 tablets/day.
Onset of Action / Duration
Onset: 2-3 hours, Duration: 6-8 hours
Special Populations
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Not recommended in pregnancy; safety in lactation not established.
Key Drug Interactions
- CYP2D6 inhibitors
- Carbamazepine
- MAO-inhibitors
- Warfarin
Contraindications
- Hypersensitivity to tramadol or paracetamol
- Severe liver impairment
- Respiratory depression
Common side effects
- Dizziness
- Nausea
- Somnolence
- Constipation
- Headache
Counselling Points
- Do not exceed recommended dose
- Avoid alcohol
- Monitor for signs of overdose
- Inform about serious skin reactions
Serious warnings
- Risk of overdose leading to severe liver damage
- Potential for seizures
- Dependence potential
Important Disclaimer
The Tramacet 37.5 mg / 25 mg Tablets professional information leaflet below is the property of Janssen Pharmaceutica and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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